Genetic Diversity Of 21 Autosomic Str-Markers Of The Codis System In Populations Of Eastern Europe

For the first time, genetic characteristics of 15 local populations of eight ethnic groups of Eastern Europe were obtained using an expanded panel that included 21 autosomal STR markers used in forensic practice for DNA identification and kinship establishment. The assessment of polymorphism of markers in the Russian, Belarusian, and Moldovan populations was carried out, and the levels of intra- and interpopulation genetic differentiation of the studied population groups were characterized. The parameters of the informational significance of the system of autosomal microsatellites for expert DNA identification and establishment of kinship were estimated. A database of allele frequencies of autosomal STR loci has been developed, which can be used to carry out probabilistic and statistical calculations when assessing the level of reliability of an expert study in the countries of the Union State. It was shown that population genetic structure should be taking into account in forensic DNA analysis.

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