The heterogeneity of non-motor symptoms in patients with Parkinson's disease in Tomsk region

The prevalence of non-motor symptoms (NMS) and the association between various motor and non-motor symptoms and quality of life in patients with Parkinson's disease (PD) in the Tomsk region were studied. Each PD patient had eight different individual NMS on average. The most common among them were constipation, depression, sleep disturbance anxiety, apathy, and impulsive behavioral disorders. There was a significant association between the quality of life and severity of anxiety, depression, apathy, UPDRS III assessment, Hoehn and Yahr scale stage, disease duration, and levodopa equivalent dosage.

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